user::28ddac12-5e10-47d0-85f5-84cf7e8e1363

Medical Paper


  1. Choi SH, Kim WJ, Lee CH, Chae KJ, Bak SH, Kwon SO, Jin KY. A 3D-CNN model with CT-based parametric response mapping for classifying COPD subjects. Sci Rep accepted
  2. Kim JH, Kim J, Kim WJ, Choi YH, Yang SR, Hong SH, Diesel particulate matter 2.5 induces epithelial-to-mesenchymal transition and upregulation of SARS-CoV-2 receptor during human pluripotent stem cell-derived alveolar organoid development. Int J Environ Res Public Health 2020;17:8410
  3. Jo HS, Jeong S, Kim WJ, Park S, Yu SA. Development of a transitional care model program for patients with pneumonia, asthma, and chronic obstructive pulmonary disease: In-depth interviews with readmitted patients. J Korean Med Sci 2020;35:e352
  4. Bak SH, Kim JH, Jin H, Kwon SO, Kim B, Cha YK, Kim WJ. Emphysema quantification using low-dose computed tomography with deep learning-based kernel conversion comparison. Eur Radiol 2020;30:6779-87
  5. Kwon SO, Hong SH, Han YJ, Bak SH, Kim J, Lee MK, London SJ, Kim WJ, Kim SY. Long-term exposure to PM10 and NO2 in relation to lung function and imaging phenotypes in a COPD cohort. Respir Res 2020;21:247
  6. Lee SA, Joshi P, Kim Y, Kang D, Kim WJ. The association of dietary macronutrients with lung function in healthy adults using the Ansan-Ansung cohort study. Nutrients 2020;12:2688
  7. Park B, An J, Kim W, Kang HY, Koh SB, Oh B, Jung KJ, Jee SH, Kim WJ, Cho MH, Silverman EK, Park T, Won S. Effects of 6p21 region on lung function is modified by smoking: a genome-wide interaction study. Sci Rep 2020;10:13075
  8. Moll M, Sakornsakolpat P, Shrine N, Hobbs BD, DeMeo DL, John C, Guyatt AL, McGeachie MJ, Gharib SA, Obeidat M, Lahousse L, Wijnant SRA, Brusselle G, Meyers DA, Bleecker ER, Li X, Tal-Singer R, Manichaikul A, Rich SS, Won S, Kim WJ, Do AR, Washko GR, Barr RG, Psaty BM, Bartz TM, Hansel NN, Barnes K, Hokanson JE, Crapo JD, Lynch D, Bakke P, Gulsvik A, Hall IP, Wain L; International COPD Genetics Consortium; SpiroMeta Consortium, Weiss ST, Silverman EK, Dudbridge F, Tobin MD, Cho MH. Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts. Lancet Respir Med 2020;8:696-708
  9. Kang J, Oh YM, Lee JH, Kim EK, Lim SY, Kim WJ, Yoon HI, Kim TH, Park TS, Kim SO, Lee SW, Lee WD, Lee JS. Distinctive patterns of pulmonary function change according to baseline lung volume and diffusing capacity. Int J Tuberc Lung Dis 2020;24:597-605
  10. Kim T, Cho HB, Kim WJ, Lee CH, Chae KJ, Choi SH, Lee KE, Bak SH, Kwon SO, Jin GY, Choi J, Park EK, Lin CL, Hoffman EA, Choi S. Quantitative CT-based structural alterations of segmental airways in cement dust-exposed subjects. Respir Res 2020;21:133
  11. Park J, Kwon SO, Kim SH, Kim SJ, Koh EJ, Won S, Kim WJ, Hang SY. Methylation quantitative trait loci analysis in Korean exposome study. Mol Cell Toxicol 2020;16:175-83
  12. Moon DH, Kwon SO, Kim SY, Kim WJ. Air pollution and incidence of lung cancer by histologic type in Korean adults: A Korean National Health Insurance Service Health Examinee Cohort Study. Int J Environ Res Public Health 2020;17:915
  13. Lee H, Choi H, Sim YS, Park S, Kim WJ, Yoo KH, Lee SJ, Kim TH, Yang B, Jeong I, Um SJ, Kim DK, Lee JH, Kwon BS, Cho YJ, Park HY, Lee CH, Rhee CK, Lee SH, Na JO, Jang AS, Jung JY, Ra SW, Lee JH, Kim SH, Kim C, Kim Y, Lee CY, Kim HK, Lee JS, Lee SW, Oh YM. KMBARC registry: protocol for a multicenter observational cohort study on non-cystic fibrosis bronchiectasis in Korea. BMJ Open 2020;10:e034090
  14. Choi HS, Park YB, Yoon HK, Lim SY, Kim TH, Park JH, Lee WY, Park SJ, Lee SW, Kim WJ, Kim KU, Shin KC, Kim DJ, Kim TE, Yoo KH, Shim JJ, Hwang YI. Validation of previous spirometric reference equations and new equations. J Korean Med Sci 2019;34;e304
  15. Schraufnagel DE, Balmes JR, Matteis SD, Hoffman B, Kim WJ, Perez-Padilla R, Rice M, Sood A, Vanker A, Wuebbles DJ. Health benefits of air pollution reduction. Ann Am Thorac Soc 2019;16:1478-87
  16. Kim J, Kim WJ, Ha KS, Han ET, Park WS, Yang SR, Hong SH. Perivascular stem cells suppress inflammasome activation during inflammatory responses in macrophages. Int J Stem Cells 2019;12:419-29
  17. Bak SH, Kwon SO, Han SS, Kim WJ. Computed tomography-derived area and density of pectoralis muscle associated disease severity and longitudinal changes in chronic obstructive pulmonary disease: a case control study. Respir Res 2019;20:226
  18. Han Y, Heo Y, Hong Y, Kwon SO, Kim WJ. Correlation between physical activity and lung function in dusty areas: Results from the chronic obstructive pulmonary disease in dusty areas (CODA) cohort. Tuberc Respir Dis 2019;82:311-8
  19. Hong Y, Choi HM, Cheong HS, Shin HD, Choi CM, Kim WJ. Epigenome-wide association analysis of differentially methylated signals in blood samples of patients with non-small cell lung cancer. J Clin Med 2019;8:E1307
  20. Kim J, Kim DY, Heo HR, Choi SS, Hong SH, Kim WJ. Role of miRNA-181a-2-3p in cadmium-induced inflammatory responses of human bronchial epithelial cells. J Thorac Dis 2019;11:3055-69
  21. Jeong KS, Kim S, Kim WJ, Kim HC, Bae J, Hong YC, Ha M, Ahn K, Lee JY, Kim Y, Ha E. Cohort profile: Beyond birth cohort study – The Korean Children’s Environmental health Study (Ko-CHENS). Environ Res 2019;172:358-66
  22. Kim DY, Kim WJ, Kim JH, Hong SH, Choi SS. Identification of putative regulatory alterations leading to changes in gene expression in chronic obstructive pulmonary disease. Mol Cells 2019;42:321-32
  23. Moon DH, Kwon SO, Kim WJ, Hong Y. Identification of serial DNA methylation changes in the blood samples of patients with lung cancer. Tuberc Respir Dis 2019;82:126-32
  24. North CM, Rice MB, Ferkol T, Gozal D, Hui C, Jung SH, Kuribayashi K, McCormack MC, Mishima M, Morimoto Y, Song Y, Wilson KC, Kim WJ, Fong KM. Air pollution in the Asia-Pacific region: A joint APSR/ATS perspective. Am J Respir Crit Care Med. 2019;199:603-700
  25. Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao D, Bartz TM, Kim DK, Lee MK, Latourelle JC, Li X, Morrow JD, Obeidat M, Wyss AB, Bakke P, Barr RG, Beaty TH, Belinsky SA, Brusselle GG, Crapo JD, de Jong K, DeMeo DL, Fingerlin TE, Gharib SA, Gulsvik A, Hall IP, Hokanson JE, Kim WJ, Lomas DA, London SJ, Meyers DA, O'Connor GT, Rennard SI, Schwartz DA, Sliwinski P, Sparrow D, Strachan DP, Tal-Singer R, Tesfaigzi Y, Vestbo J, Vonk JM, Yim JJ, Zhou X, Bossé Y, Manichaikul A, Lahousse L, Silverman EK, Boezen HM, Wain LV, Tobin MD, Hobbs BD, Cho MH. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Nat Genet 2019;51:494-505
  26. Lee MK, Xu CJ, Carnes MU, Nichols CE, Ward JM, Kwon SO, Kim SY, Kim WJ, London SJ. Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean Adults. Clin Epigenetics 2019;11:37
  27. Hong Y, Kim Y, Lee JJ, Lee MG, Lee CY, Kim Y, Heo J, Han SS, Lee SJ, Kim WJ, Hong JY. Levels of vitamin D-associated cytokines distinguish between active and latent tuberculosis following a tuberculosis outbreak. BMC Infect Dis 2019;19:151
  28. Heo HR, Kim J, Kim WJ, Yang SR, Han SS, Lee SJ, Hong Y, Hong SH. Human pluripotent stem cell-derived alveolar epithelial cells are alternatives for in vitro pulmotoxicity assessment. Sci Rep 2019;9:505
  29. Lee J, Lee H, Jang S, Hong SH, Kim WJ, Ryu SM, Park SM, Lee KH, Cho SJ, Yang SR. CMIT/MIT induce apoptosis and inflammation in alveolar epithelial cells through p38/JNK/ERK1/2 signaling pathway. Mol Cell Toxicol 2019;15:41-8
  30. Heo HR, Song H, Kim HR, Lee JE, Chung YG, Kim WJ, Yang SR, Kim KS, Chun T, Lee DR, Hong SH. Reprogramming mechanisms influence the maturation of hematopoietic progenitors from human pluripotent stem cells. Cell Death Dis 2018;9:1090
  31. Oh YM, Lee KS, Hong YK, Hwang SC, Kim JY, Kim DK, Yoo KH, Lim SY, Rhee CK, Yoon HK, Lee SY, Park YB, Jung JH, Kim WJ, Lee SD, Park JH. Blood eosinophil count as a prognostic biomarker in COPD, Int J Chron Obstruct Pulmon Dis 13:3589-96
  32. Song JH, Lee CH, Kim DK, Yoon HK, Byun MK, Rhee CK, Lee JC, Kim WJ, Hwang YI, Yoo KH, Jung KS. Differences in prevalence of asthma-COPD overlap according to different criteria, Medicine 2018; 97:e12049
  33. Jung CY, Choe YH, Lee SY, Kim WJ, Lee JD, Ra SW, Choi EG, Lee JS, Park MJ, Na JO. Use of serology and polymerase chain reaction to detect atypical respiratory pathogens during acute exacerbation on chronic obstructive pulmonary disease, Korean J Intern Med 2018;33:941-51
  34. Jo YS, Kwon SO, Kim J, Kim WJ. Neutrophil gelatinase-associated lipocalin as a complementary biomarker for the asthma-chronic obstructive pulmonary disease overlap, J Thorac Dis 2018;10:5047-56
  35. Jeong I, Lim JH, Oh DK, Kim WJ, Oh YM. Gene expression profile of human lung in a relatively early stage of COPD with emphysema, Int J Chron Obstruct Pulmon Dis 2018:13 2643-55
  36. Kwon JW, Park HW, Kim WJ, Kim MG, Lee SJ. Exposure to volatile organic compounds and airway inflammation. Environ Health 2018;17:65
  37. Wyss AB, Sofer T, Lee MK, Terzikhan N, Nguyen JN, Lahousse L, Latourelle JC, Smith AV, Bartz TM, Feitosa MF, Gao W, Ahluwalia TS, Tang W, Oldmeadow C, Duan Q, de Jong K, Wojczynski MK, Wang XQ, Noordam R, Hartwig FP, Jackson VE, Wang T, Obeidat M, Hobbs BD, Huan T, Gui H, Parker MM, Hu D, Mogil LS, Kichaev G, Jin J, Graff M, Harris TB, Kalhan R, Heckbert SR, Paternoster L, Burkart KM, Liu Y, Holliday EG, Wilson JG, Vonk JM, Sanders JL, Barr RG, de Mutsert R, Menezes AMB, Adams HHH, van den Berge M, Joehanes R, Levin AM, Liberto J, Launer LJ, Morrison AC, Sitlani CM, Celedón JC, Kritchevsky SB, Scott RJ, Christensen K, Rotter JI, Bonten TN, Wehrmeister FC, Bossé Y, Xiao S, Oh S, Franceschini N, Brody JA, Kaplan RC, Lohman K, McEvoy M, Province MA, Rosendaal FR, Taylor KD, Nickle DC, Williams LK, Burchard EG, Wheeler HE, Sin DD, Gudnason V, North KE, Fornage M, Psaty BM, Myers RH, O'Connor G, Hansen T, Laurie CC, Cassano PA, Sung J, Kim WJ, Attia JR, Lange L, Boezen HM, Thyagarajan B, Rich SS, Mook-Kanamori DO, Horta BL, Uitterlinden AG, Im HK, Cho MH, Brusselle GG, Gharib SA, Dupuis J, Manichaikul A, London SJ. Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Nat Commun 2018;9:2976
  38. Shin SH, Park HY, Kang D, Cho J, Kwon SO, Park JH, Lee JS, Oh YM, Sin DD, Kim WJ, Lee SD. Serial blood eosinophils and clinical outcome in patients with chronic obstructive pulmonary disease. Respir Res 2018;19:134
  39. Kim WJ, Gupta V, Nishimura M, Makita H, Idolor L, Roa C, Loh LC, Ong CK, Wang JS, Boonsawat W, Gunasekera KD, Madegedara D, Kuo HP, Wang CH, Wang C, Yang T, Lin YX, Ko FWS, Hui DSC, Lan LTT, Vu QTT, Bhome AB, Ng A, Seo JB, Lee BY, Lee JS, Oh YM, Lee SD. Identification of chronic obstructive pulmonary disease subgroups in 13 Asian cities. Int J Tuberc Lung Dis 2018;22:820-6
  40. Hong Y, Hong SH, Oh YM, Shin SH, Choi SS, Kim WJ. Identification of lung cancer specific differentially methylated regions using genome-wide DNA methylation study. Mol Cell Toxicol 2018;14:315-22
  41. Kim DJ, Kim WJ, Lim MN, Hong Y, Lee SJ, Hong SH, Heo J, Lee HY, Han SS. Plasma CRABP2 as a novel biomarker in patients with non-small cell lung cancer. J Korean Med Sci 2018;33:e178
  42. Lee H, Hong Y, Lim MN, Bak SH, Kim MJ, Kim K, Kim WJ, Park HY. Inflammatory biomarkers and radiologic measurements in never-smokers with COPD: A cross-sectional study from the CODA cohort. Chr Respir Dis 2018;15:138-45
  43. Bak SH, Kim S, Hong Y, Heo J, Lim MN, Kim WJ. Quantitative computed tomography features and clinical manifestations associated with the extent of bronchiectasis in patients with moderate-to-severe COPD. Int J Chron Obstruct Pulmon Dis 2018;13:1421-31
  44. Ji W, Lim MN, Bak SH, Hong SH, Han SS, Lee SJ, Kim WJ, Hong Y. Differences in chronic obstructive pulmonary disease phenotypes between non-smokers and smokers. Clin Respir J 2018;12:666-673
  45. Lee SR, Kim WT, Kim TN, Nam JK, Kim WJ, Leem SH. Association between the length of the MUC8-minisatellite 5 region and susceptibility to chronic obstructive pulmonary disease. Genes Genome 2018;40:123-7
  46. Kim WJ, Park HJ, Choi YJ, Kwon EY, Kim BM, Lee JH, Chang JH, Kang JL, Choi JH. Association between genetic variations of MERTK and chronic obstructive pulmonary disease in Koreans. J Korean Med Sci 2018;33:e56
  47. Jo YS, Lim MN, Han YJ, Kim WJ. Epidemiological study of PM2.5 and risk of COPD-related hospital visits and association with particle constituents in Chuncheon, Korea. Int J Chron Obstruct Pulmon Dis 2018;13:299-307